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BIB
2006
169views more  BIB 2006»
13 years 8 months ago
Bio-ontologies: current trends and future directions
: In recent years, as a knowledge-based discipline, bioinformatics has moved to make its knowledge more computationally amenable. After its beginnings in the disciplines as a techn...
Olivier Bodenreider, Robert Stevens
BMCBI
2006
82views more  BMCBI 2006»
13 years 8 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
BMCBI
2006
111views more  BMCBI 2006»
13 years 8 months ago
SIMMAP: Stochastic character mapping of discrete traits on phylogenies
Background: Character mapping on phylogenies has played an important, if not critical role, in our understanding of molecular, morphological, and behavioral evolution. Until very ...
Jonathan P. Bollback
BMCBI
2006
122views more  BMCBI 2006»
13 years 8 months ago
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
BMCBI
2006
211views more  BMCBI 2006»
13 years 8 months ago
Missing value estimation for DNA microarray gene expression data by Support Vector Regression imputation and orthogonal coding s
Background: Gene expression profiling has become a useful biological resource in recent years, and it plays an important role in a broad range of areas in biology. The raw gene ex...
Xian Wang, Ao Li, Zhaohui Jiang, Huanqing Feng