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BMCBI
2007
134views more  BMCBI 2007»
15 years 2 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
BMCBI
2010
121views more  BMCBI 2010»
15 years 2 months ago
MS4 - Multi-Scale Selector of Sequence Signatures: An alignment-free method for classification of biological sequences
Background: While multiple alignment is the first step of usual classification schemes for biological sequences, alignment-free methods are being increasingly used as alternatives...
Eduardo Corel, Florian Pitschi, Ivan Laprevotte, G...
BMCBI
2008
155views more  BMCBI 2008»
15 years 2 months ago
ComPath: comparative enzyme analysis and annotation in pathway/subsystem contexts
Background: Once a new genome is sequenced, one of the important questions is to determine the presence and absence of biological pathways. Analysis of biological pathways in a ge...
Kwangmin Choi, Sun Kim
BMCBI
2007
91views more  BMCBI 2007»
15 years 2 months ago
A machine learning approach for the identification of odorant binding proteins from sequence-derived properties
Background: Odorant binding proteins (OBPs) are believed to shuttle odorants from the environment to the underlying odorant receptors, for which they could potentially serve as od...
Ganesan Pugalenthi, E. Ke Tang, Ponnuthurai N. Sug...
BMCBI
2008
84views more  BMCBI 2008»
15 years 2 months ago
poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening
Background: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug di...
Raghunandan M. Kainkaryam, Peter J. Woolf
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