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BMCBI
2006
125views more  BMCBI 2006»
13 years 9 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...
BMCBI
2005
126views more  BMCBI 2005»
13 years 9 months ago
An algorithm for automatic evaluation of the spot quality in two-color DNA microarray experiments
Background: Although DNA microarray technologies are very powerful for the simultaneous quantitative characterization of thousands of genes, the quality of the obtained experiment...
Eugene Novikov, Emmanuel Barillot
BMCBI
2007
122views more  BMCBI 2007»
13 years 9 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
KBSE
2002
IEEE
14 years 1 months ago
Process Support for Tools Interoperability
Commercial tools are heavily used, relatively cheap, well maintained, and provide powerful functionalities. However, composing these tools in order to build larger applications ra...
Anh-Tuyet Le
BMCBI
2008
130views more  BMCBI 2008»
13 years 9 months ago
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yus...