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BMCBI
2004
229views more  BMCBI 2004»
13 years 7 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...
BMCBI
2008
163views more  BMCBI 2008»
13 years 7 months ago
Gene Ontology term overlap as a measure of gene functional similarity
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...
Meeta Mistry, Paul Pavlidis
BMCBI
2007
129views more  BMCBI 2007»
13 years 7 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
CBMS
2008
IEEE
13 years 9 months ago
Generating GO Slim Using Relational Database Management Systems to Support Proteomics Analysis
The Gene Ontology Consortium built the Gene Ontology database (GO) to address the need for a common standard in naming genes and gene products. Using different names for the same ...
Getiria Onsongo, Hongwei Xie, Timothy J. Griffin, ...
BMCBI
2006
186views more  BMCBI 2006»
13 years 7 months ago
Systematic gene function prediction from gene expression data by using a fuzzy nearest-cluster method
Background: Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments....
Xiaoli Li, Yin-Chet Tan, See-Kiong Ng