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APBC
2004
116views Bioinformatics» more  APBC 2004»
13 years 9 months ago
Structure-Function Relationship in DNA Sequence Recognition by Transcription Factors
Transcription factors play essential role in the gene regulation in higher organisms, binding to multiple target sequences and regulating multiple genes in a complex manner. In or...
Akinori Sarai, Samuel Selvaraj, M. Michael Gromiha...
RECOMB
2003
Springer
14 years 8 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
IEEEICCI
2006
IEEE
14 years 1 months ago
Using Feature Selection Filtering Methods for Binding Site Predictions
Currently the best algorithms for transcription factor binding site prediction are severely limited in accuracy. In previous work we applied classification techniques on predictio...
Yi Sun, Mark Robinson, Rod Adams, Rene te Boekhors...
BMCBI
2007
164views more  BMCBI 2007»
13 years 7 months ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason
NAR
2006
84views more  NAR 2006»
13 years 7 months ago
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are spec...
Jeffrey G. Mandell, Carlos F. Barbas III