Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
Background: Mixture models of mutagenetic trees are evolutionary models that capture several pathways of ordered accumulation of genetic events observed in different subsets of pa...
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...