Sciweavers

175 search results - page 10 / 35
» Predicting the Effects of Gene Deletion
Sort
View
BMCBI
2008
94views more  BMCBI 2008»
13 years 7 months ago
Conserved co-expression for candidate disease gene prioritization
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
Martin Oti, Jeroen van Reeuwijk, Martijn A. Huynen...
BMCBI
2008
160views more  BMCBI 2008»
13 years 7 months ago
A method for analyzing censored survival phenotype with gene expression data
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
Tongtong Wu, Wei Sun, Shinsheng Yuan, Chun-Houh Ch...
RECOMB
2008
Springer
14 years 7 months ago
Constructing Treatment Portfolios Using Affinity Propagation
A key problem of interest to biologists and medical researchers is the selection of a subset of queries or treatments that provide maximum utility for a population of targets. For ...
Delbert Dueck, Brendan J. Frey, Nebojsa Jojic, Vla...
BMCBI
2007
120views more  BMCBI 2007»
13 years 7 months ago
Recognition of interferon-inducible sites, promoters, and enhancers
Background: Computational analysis of gene regulatory regions is important for prediction of functions of many uncharacterized genes. With this in mind, search of the target genes...
Elena A. Ananko, Yury V. Kondrakhin, Tatyana I. Me...
BMCBI
2010
114views more  BMCBI 2010»
13 years 7 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...