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BMCBI
2006
126views more  BMCBI 2006»
13 years 7 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
Scaffold filling, contig fusion and comparative gene order inference
Background: There has been a trend in increasing the phylogenetic scope of genome sequencing without finishing the sequence of the genome. Increasing numbers of genomes are being ...
Adriana Muñoz, Chunfang Zheng, Qian Zhu, Vi...
GECCO
2004
Springer
164views Optimization» more  GECCO 2004»
14 years 24 days ago
Fuzzy Dominance Based Multi-objective GA-Simplex Hybrid Algorithms Applied to Gene Network Models
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
BMCBI
2005
106views more  BMCBI 2005»
13 years 7 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...
AB
2008
Springer
14 years 1 months ago
An Algorithm for Qualitative Simulation of Gene Regulatory Networks with Steep Sigmoidal Response Functions
A specific class of ODEs has been shown to be adequate to describe the essential features of the complex dynamics of Gene-Regulatory Networks (GRN). But, the effective exploitatio...
Liliana Ironi, Luigi Panzeri, Erik Plahte