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» Predicting the Effects of Gene Deletion
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RECOMB
2005
Springer
14 years 7 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
JIB
2006
220views more  JIB 2006»
13 years 7 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
BIB
2007
59views more  BIB 2007»
13 years 7 months ago
Statistically designing microarrays and microarray experiments to enhance sensitivity and specificity
Gene expression signatures from microarray experiments promise to provide important prognostic tools for predicting disease outcome or response to treatment. A number of microarra...
Jason C. Hsu, Jane Chang, Tao Wang, Eiríkur...
RECOMB
2003
Springer
14 years 7 months ago
Combining phylogenetic and hidden Markov models in biosequence analysis
A few models have appeared in recent years that consider not only the way substitutions occur through evolutionary history at each site of a genome, but also the way the process c...
Adam C. Siepel, David Haussler
NAR
2011
245views Computer Vision» more  NAR 2011»
12 years 10 months ago
The Comparative Toxicogenomics Database: update 2011
The Comparative Toxicogenomics Database (CTD) is a public resource that promotes understanding about the interaction of environmental chemicals with gene products, and their effec...
Allan Peter Davis, Benjamin L. King, Susan Mockus,...