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» Predicting the beta-helix fold from protein sequence data
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BMCBI
2007
129views more  BMCBI 2007»
13 years 8 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
BMCBI
2008
149views more  BMCBI 2008»
13 years 8 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
ISDA
2009
IEEE
14 years 3 months ago
MAHATMA: A Genetic Programming-Based Tool for Protein Classification
Proteins can be grouped into families according to some features such as hydrophobicity, composition or structure, aiming to establish common biological functions. This paper pres...
Denise Fukumi Tsunoda, Alex Alves Freitas, Heitor ...
BMCBI
2007
104views more  BMCBI 2007»
13 years 9 months ago
TISs-ST: a web server to evaluate polymorphic translation initiation sites and their reflections on the secretory targets
Background: The nucleotide sequence flanking the translation initiation codon (start codon context) affects the translational efficiency of eukaryotic mRNAs, and may indicate the ...
Renato Vicentini, Marcelo Menossi
BMCBI
2007
126views more  BMCBI 2007»
13 years 9 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne