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BMCBI
2010
127views more  BMCBI 2010»
13 years 7 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BMCBI
2004
123views more  BMCBI 2004»
13 years 7 months ago
Interaction profile-based protein classification of death domain
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Drew Lett, Michael Hsing, Frederic Pio
BMCBI
2010
97views more  BMCBI 2010»
13 years 7 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
AAAI
2007
13 years 9 months ago
A Randomized String Kernel and Its Application to RNA Interference
String kernels directly model sequence similarities without the necessity of extracting numerical features in a vector space. Since they better capture complex traits in the seque...
Shibin Qiu, Terran Lane, Ljubomir J. Buturovic
KDD
2009
ACM
132views Data Mining» more  KDD 2009»
14 years 8 months ago
Learning patterns in the dynamics of biological networks
Our dynamic graph-based relational mining approach has been developed to learn structural patterns in biological networks as they change over time. The analysis of dynamic network...
Chang Hun You, Lawrence B. Holder, Diane J. Cook