Abstract. We investigate the problem of inferring contiguous ancestral regions (CARs) of the genome of the last common ancestor of all extant amniotes, based on the currently seque...
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
Jian Ma, Aakrosh Ratan, Brian J. Raney, Bernard B....
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorith...
In 2006, a debate has risen on the question of the efficiency of bioinformatics methods to reconstruct mammalian ancestral genomes. Three years later, Gordon et al. (PLoS Genetics,...
We have developed a hidden Markov model (HMM)to detect the protein coding regions within one megabase contiguous sequence data, registered in a database called GenBankin eight ent...