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BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...
BMCBI
2006
146views more  BMCBI 2006»
13 years 8 months ago
GeneTools - application for functional annotation and statistical hypothesis testing
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
Vidar Beisvag, Frode K. R. Jünge, Hallgeir Be...
BIOCOMP
2008
13 years 10 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
CIBCB
2005
IEEE
14 years 2 months ago
Functional Distances for Genes Based on GO Feature Maps and their Application to Clustering
— With the invention of high throughput methods, researchers are capable of producing large amounts of biological data. During the analysis of such data, the need for a functiona...
Nora Speer, Holger Fröhlich, Christian Spieth...
BMCBI
2008
170views more  BMCBI 2008»
13 years 8 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou