High-quality annotation of biological data is central to bioinformatics. Annotation using terms from ontologies provides reliable computational access to data. The Gene Ontology (...
Michael Bada, Daniele Turi, Robin McEntire, Robert...
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Background: Various measures of semantic similarity of terms in bio-ontologies such as the Gene Ontology (GO) have been used to compare gene products. Such measures of similarity ...
Brendan Sheehan, Aaron J. Quigley, Benoit Gaudin, ...
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
Annotating genes and their products with Gene Ontology codes is an important area of research. One approach for doing this is to use the information available about these genes in...