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SIGMOD
2004
ACM
88views Database» more  SIGMOD 2004»
14 years 8 months ago
Using Reasoning to Guide Annotation with Gene Ontology Terms in GOAT
High-quality annotation of biological data is central to bioinformatics. Annotation using terms from ontologies provides reliable computational access to data. The Gene Ontology (...
Michael Bada, Daniele Turi, Robin McEntire, Robert...
BMCBI
2005
114views more  BMCBI 2005»
13 years 8 months ago
Systematic analysis of human kinase genes: a large number of genes and alternative splicing events result in functional and stru
Background: Protein kinases are a well defined family of proteins, characterized by the presence of a common kinase catalytic domain and playing a significant role in many importa...
Luciano Milanesi, Mauro Petrillo, Leandra Sepe, An...
BMCBI
2008
124views more  BMCBI 2008»
13 years 8 months ago
A relation based measure of semantic similarity for Gene Ontology annotations
Background: Various measures of semantic similarity of terms in bio-ontologies such as the Gene Ontology (GO) have been used to compare gene products. Such measures of similarity ...
Brendan Sheehan, Aaron J. Quigley, Benoit Gaudin, ...
BMCBI
2011
13 years 3 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
BMCBI
2007
123views more  BMCBI 2007»
13 years 8 months ago
GO for gene documents
Annotating genes and their products with Gene Ontology codes is an important area of research. One approach for doing this is to use the information available about these genes in...
Padmini Srinivasan, Xin Ying Qiu