Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
: We propose a domain-based classification method to predict protein-protein interactions using probabilities of putative interacting domain pairs derived from both experimentally-...
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
Background: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure ...