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» Prediction of Protein Function Using Protein-Protein Interac...
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130
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CSB
2005
IEEE
133views Bioinformatics» more  CSB 2005»
15 years 8 months ago
Biological Pathway Prediction from Multiple Data Sources Using Iterative Bayesian Updating
There is a diversity of functional genomics data, such as gene expression data from microarray experiments, phenotypic data from gene deletion experiments, protein-protein interac...
Corey Powell, Joshua M. Stuart
85
Voted
NAR
2007
149views more  NAR 2007»
15 years 2 months ago
UniHI: an entry gate to the human protein interactome
Systematic mapping of protein–protein interactions has become a central task of functional genomics. To map the human interactome, several strategies have recently been pursued....
Gautam Chaurasia, Yasir Iqbal, Christian Häni...
113
Voted
BMCBI
2010
95views more  BMCBI 2010»
15 years 2 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
130
Voted
BMCBI
2006
152views more  BMCBI 2006»
15 years 2 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
NAR
2011
207views Computer Vision» more  NAR 2011»
14 years 5 months ago
PSORTdb - an expanded, auto-updated, user-friendly protein subcellular localization database for Bacteria and Archaea
The subcellular localization (SCL) of a microbial protein provides clues about its function, its suitability as a drug, vaccine or diagnostic target and aids experimental design. ...
Nancy Y. Yu, Matthew R. Laird, Cory Spencer, Fiona...