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» Prediction of indirect interactions in proteins
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BMCBI
2008
83views more  BMCBI 2008»
13 years 7 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
RECOMB
2008
Springer
14 years 7 months ago
Fast and Accurate Alignment of Multiple Protein Networks
Comparative analysis of protein networks has proven to be a powerful approach for elucidating network structure and predicting protein function and interaction. A fundamental chall...
Maxim Kalaev, Vineet Bafna, Roded Sharan
BMCBI
2005
118views more  BMCBI 2005»
13 years 7 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
BMCBI
2010
127views more  BMCBI 2010»
13 years 7 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
RECOMB
2009
Springer
14 years 8 months ago
Finding Biologically Accurate Clusterings in Hierarchical Tree Decompositions Using the Variation of Information
Abstract. Hierarchical clustering is a popular method for grouping together similar elements based on a distance measure between them. In many cases, annotation information for som...
Saket Navlakha, James Robert White, Niranjan Nagar...