346 search results - page 52 / 70 » Prediction of indirect interactions in proteins |
APBC
2004
13 years 8 months ago
2004
Transcription factors play essential role in the gene regulation in higher organisms, binding to multiple target sequences and regulating multiple genes in a complex manner. In or...
JCC
2008
13 years 6 months ago
2008
: The prediction of the binding free energy between a ligand and a protein is an important component in the virtual screening and lead optimization of ligands for drug discovery. T...
NAR
2008
13 years 7 months ago
2008
The molecular basis of drug action is often not well understood. This is partly because the very abundant and diverse information generated in the past decades on drugs is hidden ...
FLAIRS
2008
13 years 9 months ago
2008
1 In this paper, we propose a peptide folding prediction method which discovers contrast patterns to differentiate and predict peptide folding classes. A contrast pattern is defin...
BMCBI
2007
13 years 7 months ago
2007
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...