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BMCBI
2007
153views more  BMCBI 2007»
13 years 6 months ago
A new pairwise kernel for biological network inference with support vector machines
Background: Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-pro...
Jean-Philippe Vert, Jian Qiu, William Stafford Nob...
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
14 years 1 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
BMCBI
2010
147views more  BMCBI 2010»
13 years 6 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
BIODATAMINING
2008
163views more  BIODATAMINING 2008»
13 years 6 months ago
Multivariate profiling of neurodegeneration-associated changes in a subcellular compartment of neurons via image processing
Background: Dysfunction in the endolysosome, a late endosomal to lysosomal degradative intracellular compartment, is an early hallmark of some neurodegenerative diseases, in parti...
Saravana K. Kumarasamy, Yunshi Wang, Vignesh Viswa...
BIOINFORMATICS
2011
13 years 1 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj