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BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
Mining prokaryotic genomes for unknown amino acids: a stop-codon-based approach
Background: Selenocysteine and pyrrolysine are the 21st and 22nd amino acids, which are genetically encoded by stop codons. Since a number of microbial genomes have been completel...
Masashi Fujita, Hisaaki Mihara, Susumu Goto, Nobuy...
GECCO
2008
Springer
135views Optimization» more  GECCO 2008»
13 years 8 months ago
Evolving sequence patterns for prediction of sub-cellular locations of eukaryotic proteins
A genetic algorithm (GA) is utilised to discover known and novel PROSITE-like sequence templates that can be used to classify the sub-cellular location of eukaryotic proteins. Whi...
Greg Paperin
BMCBI
2006
112views more  BMCBI 2006»
13 years 7 months ago
Protein disorder prediction by condensed PSSM considering propensity for order or disorder
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
Chung-Tsai Su, Chien-Yu Chen, Yu-Yen Ou
BMCBI
2002
81views more  BMCBI 2002»
13 years 7 months ago
Species-specific protein sequence and fold optimizations
Background: An organism's ability to adapt to its particular environmental niche is of fundamental importance to its survival and proliferation. In the largest study of its k...
Michel Dumontier, Katerina Michalickova, Christoph...
BMCBI
2008
89views more  BMCBI 2008»
13 years 7 months ago
An incremental approach to automated protein localisation
Background: The subcellular localisation of proteins in intact living cells is an important means for gaining information about protein functions. Even dynamic processes can be ca...
Marko Tscherepanow, Nickels Jensen, Franz Kummert