Finding recurring residue packing patterns, or spatial motifs, that characterize protein structural families is an important problem in bioinformatics. To this end, we apply a nov...
Jun Huan, Wei Wang 0010, Deepak Bandyopadhyay, Jac...
Background: Contact order is a topological descriptor that has been shown to be correlated with several interesting protein properties such as protein folding rates and protein tr...
Yi Shi, Jianjun Zhou, David Arndt, David S. Wishar...
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
Abstract. Over the last decade several prediction methods have been developed for determining structural and functional properties of individual protein residues using sequence and...
Huzefa Rangwala, Christopher Kauffman, George Kary...