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GECCO
2004
Springer
132views Optimization» more  GECCO 2004»
14 years 22 days ago
Optimizing Topology and Parameters of Gene Regulatory Network Models from Time-Series Experiments
Abstract. In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. Different approaches to infer the dependencies of gene r...
Christian Spieth, Felix Streichert, Nora Speer, An...
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
13 years 7 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
ICAI
2007
13 years 8 months ago
Mining and Dynamic Simulation of Sub-Networks from Large Biomolecular Networks
Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As biomolecular...
Xiaohua Hu, Fang-Xiang Wu, Michael K. Ng, Bahrad A...
BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
Comparative study of discretization methods of microarray data for inferring transcriptional regulatory networks
Background: Microarray data discretization is a basic preprocess for many algorithms of gene regulatory network inference. Some common discretization methods in informatics are us...
Yong Li, Lili Liu, Xi Bai, Hua Cai, Wei Ji, Dianji...
BMCBI
2006
126views more  BMCBI 2006»
13 years 7 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron