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» Probabilistic annotation of protein sequences based on funct...
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NAR
2010
148views more  NAR 2010»
13 years 2 months ago
SIMAP - a comprehensive database of pre-calculated protein sequence similarities, domains, annotations and clusters
The prediction of protein function as well as the reconstruction of evolutionary genesis employing sequence comparison at large is still the most powerful tool in sequence analysi...
Thomas Rattei, Patrick Tischler, Stefan Götz,...
NAR
2011
202views Computer Vision» more  NAR 2011»
12 years 10 months ago
PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family
PREX (http://www.csb.wfu.edu/prex/) is a database of currently 3516 peroxiredoxin (Prx or PRDX) protein sequences unambiguously classified into one of six distinct subfamilies. Pe...
Laura Soito, Chris Williamson, Stacy T. Knutson, J...
BMCBI
2005
198views more  BMCBI 2005»
13 years 7 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
BIRD
2007
Springer
107views Bioinformatics» more  BIRD 2007»
14 years 1 months ago
Prediction of Structurally-Determined Coiled-Coil Domains with Hidden Markov Models
The coiled-coil protein domain is a widespread structural motif known to be involved in a wealth of key interactions in cells and organisms. Coiled-coil recognition and prediction ...
Piero Fariselli, Daniele Molinini, Rita Casadio, A...
BMCBI
2006
207views more  BMCBI 2006»
13 years 7 months ago
A new measure for functional similarity of gene products based on Gene Ontology
Background: Gene Ontology (GO) is a standard vocabulary of functional terms and allows for coherent annotation of gene products. These annotations provide a basis for new methods ...
Andreas Schlicker, Francisco S. Domingues, Jö...