Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
Background: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such...
Barry Zeeberg, Hongfang Liu, Ari B. Kahn, Martin E...
Background: An important objective of DNA microarray-based gene expression experimentation is determining interrelationships that exist between differentially expressed genes and ...
Saurin D. Jani, Gary L. Argraves, Jeremy L. Barth,...
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
We address the issue of providing highly informative annotations using information revealed by the structured vocabularies of Gene Ontology (GO). For a target, a set of candidate ...