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RECOMB
2006
Springer
14 years 8 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
RECOMB
2005
Springer
14 years 8 months ago
Towards an Integrated Protein-Protein Interaction Network
Abstract. Protein-protein interactions play a major role in most cellular processes. Thus, the challenge of identifying the full repertoire of interacting proteins in the cell is o...
Ariel Jaimovich, Gal Elidan, Hanah Margalit, Nir F...
IDEAL
2007
Springer
14 years 2 months ago
PINCoC : A Co-clustering Based Approach to Analyze Protein-Protein Interaction Networks
A novel technique to search for functional modules in a protein-protein interaction network is presented. The network is represented by the adjacency matrix associated with the und...
Clara Pizzuti, Simona E. Rombo
BMCBI
2010
142views more  BMCBI 2010»
13 years 8 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
ALMOB
2006
40views more  ALMOB 2006»
13 years 8 months ago
Probability-based model of protein-protein interactions on biological timescales
Alexander L. Tournier, Paul W. Fitzjohn, Paul A. B...