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BMCBI
2008
106views more  BMCBI 2008»
13 years 11 months ago
Searching for evolutionary distant RNA homologs within genomic sequences using partition function posterior probabilities
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
Usman Roshan, Satish Chikkagoudar, Dennis R. Lives...
NAR
2010
107views more  NAR 2010»
13 years 5 months ago
PLAST-ncRNA: Partition function Local Alignment Search Tool for non-coding RNA sequences
Alignment-based programs are valuable tools for finding potential homologs in genome sequences. Previously, it has been shown that partition function posterior probabilities attun...
Satish Chikkagoudar, Dennis R. Livesay, Usman Rosh...
BMCBI
2007
130views more  BMCBI 2007»
13 years 11 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
ICASSP
2007
IEEE
14 years 5 months ago
Toward Turbo Decoding of RNA Secondary Structure
We propose an iterative probabilistic algorithm for estimation of RNA secondary structure using sequence data from two homologous sequences. The method is intended to exploit inte...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...