Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
R. Henrik Nilsson, Balaji Rajashekar, Karl-Henrik ...
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Background: In recent years, the number of High Throughput Screening (HTS) assays deposited in PubChem has grown quickly. As a result, the volume of both the structured informatio...
Lianyi Han, Tugba O. Suzek, Yanli Wang, Steve H. B...
Easy reuse and integration of declaratively described information in a distributed setting is one of the main motivations for building the Semantic Web. Despite of this claim, reu...