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BMCBI
2004
123views more  BMCBI 2004»
13 years 10 months ago
galaxieEST: addressing EST identity through automated phylogenetic analysis
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
R. Henrik Nilsson, Balaji Rajashekar, Karl-Henrik ...
BMCBI
2008
130views more  BMCBI 2008»
13 years 11 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2002
126views more  BMCBI 2002»
13 years 10 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
BMCBI
2010
70views more  BMCBI 2010»
13 years 11 months ago
The Text-mining based PubChem Bioassay neighboring analysis
Background: In recent years, the number of High Throughput Screening (HTS) assays deposited in PubChem has grown quickly. As a result, the volume of both the structured informatio...
Lianyi Han, Tugba O. Suzek, Yanli Wang, Steve H. B...
WWW
2008
ACM
14 years 11 months ago
Networked graphs: a declarative mechanism for SPARQL rules, SPARQL views and RDF data integration on the web
Easy reuse and integration of declaratively described information in a distributed setting is one of the main motivations for building the Semantic Web. Despite of this claim, reu...
Simon Schenk, Steffen Staab