1509 search results - page 234 / 302 » Processing with cell assemblies |
BMCBI
2007
13 years 10 months ago
2007
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
BMCBI
2010
2010
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
13 years 10 months ago
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
BMCBI
2007
13 years 10 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
BMCBI
2008
13 years 10 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
BMCBI
2008
13 years 10 months ago
2008
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...