Background: The genomes of an increasing number of species are being investigated through generation of expressed sequence tags (ESTs). However, ESTs are prone to sequencing error...
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Discovery of frequent patterns has been studied in a variety of data mining settings. In its simplest form, known from association rule mining, the task is to discover all frequent...
We introduce an alternative to the smoothing technique approach for constrained optimization. As it turns out for any given smoothing function there exists a modification with part...
The Protein Information Resource (PIR; http://wwwnbrf.georgetown.edu/pir/ ) supports research on molecular evolution, functional genomics, and computational biology by maintaining...
Winona C. Barker, John S. Garavelli, Daniel H. Haf...