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BMCBI
2007
13 years 9 months ago
2007
Background: The nucleotide sequence flanking the translation initiation codon (start codon context) affects the translational efficiency of eukaryotic mRNAs, and may indicate the ...
BMCBI
2010
13 years 9 months ago
2010
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
BMCBI
2008
2008
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
13 years 9 months ago
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
BMCBI
2008
13 years 9 months ago
2008
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
BMCBI
2010
13 years 9 months ago
2010
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...