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» Progressive multiple sequence alignments from triplets
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FPL
2010
Springer
188views Hardware» more  FPL 2010»
13 years 5 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...
BMCBI
2008
178views more  BMCBI 2008»
13 years 7 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 6 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
BMCBI
2008
101views more  BMCBI 2008»
13 years 7 months ago
Scipio: Using protein sequences to determine the precise exon/intron structures of genes and their orthologs in closely related
Background: For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although a vast amount of genomic sequence data is ava...
Oliver Keller, Florian Odronitz, Mario Stanke, Mar...
CSB
2003
IEEE
14 years 27 days ago
Search for Evolution-Related-Oligonucleotides and Conservative Words in rRNA Sequences
We describe a method for finding ungapped conserved words in rRNA sequences that is effective, utilizes evolutionary information and does not depend on multiple sequence alignment...
Liaofu Luo, Li-Ching Hsieh, Fengmin Ji, Mengwen Ji...