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BMCBI
2010
97views more  BMCBI 2010»
13 years 10 months ago
SeqRate: sequence-based protein folding type classification and rates prediction
Background: Protein folding rate is an important property of a protein. Predicting protein folding rate is useful for understanding protein folding process and guiding protein des...
Guan Ning Lin, Zheng Wang, Dong Xu, Jianlin Cheng
BMCBI
2010
136views more  BMCBI 2010»
13 years 10 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2007
135views more  BMCBI 2007»
13 years 10 months ago
DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput
Background: Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by man...
Brad T. Sherman, Da Wei Huang, Qina Tan, Yongjian ...
BMCBI
2007
122views more  BMCBI 2007»
13 years 10 months ago
TAP score: torsion angle propensity normalization applied to local protein structure evaluation
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
Silvio C. E. Tosatto, Roberto Battistutta
BMCBI
2008
154views more  BMCBI 2008»
13 years 10 months ago
Extension of the COG and arCOG databases by amino acid and nucleotide sequences
Background: The current versions of the COG and arCOG databases, both excellent frameworks for studies in comparative and functional genomics, do not contain the nucleotide sequen...
Florian Meereis, Michael Kaufmann
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