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BMCBI
2010
163views more  BMCBI 2010»
13 years 7 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
BMCBI
2002
108views more  BMCBI 2002»
13 years 7 months ago
A memory-efficient dynamic programming algorithm for optimal alignment of a sequence to an RNA secondary structure
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Sean R. Eddy
BIBM
2010
IEEE
277views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Accurate prediction of ATP-binding residues using sequence and sequence-derived structural descriptors
ATP is a ubiquitous nucleotide that provides energy for cellular activities, catalyzes chemical reactions, and is involved in cellular signaling. The knowledge of the ATPprotein in...
Ke Chen 0003, Marcin J. Mizianty, Lukasz A. Kurgan
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
NAR
2011
256views Computer Vision» more  NAR 2011»
12 years 10 months ago
ModBase, a database of annotated comparative protein structure models, and associated resources
ModBase (http://salilab.org/modbase) is a database of annotated comparative protein structure models. The models are calculated by ModPipe, an automated modeling pipeline that rel...
Ursula Pieper, Benjamin M. Webb, David T. Barkan, ...