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» Protein Model Representation and Construction
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BMCBI
2002
133views more  BMCBI 2002»
13 years 8 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
BMCBI
2008
120views more  BMCBI 2008»
13 years 8 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
ISBI
2007
IEEE
14 years 2 months ago
Quantitative Representation of Three-dimensional Cell Culture Models
Three-dimensional mammary cell culture models offer new opportunities for the development of computational techniques for segmentation, localization, and multicellular organizatio...
Hang Chang, Catherine Park, Bahram Parvin
BMCBI
2006
161views more  BMCBI 2006»
13 years 8 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
BIBE
2004
IEEE
149views Bioinformatics» more  BIBE 2004»
14 years 10 days ago
Interactive 3D Protein Structure Visualization Using Virtual Reality
Large-scale biomedical data sets of macromolecular structures such as DNA and proteins describe highly complex biomolecular entities which often consist of thousands of atoms and ...
Elke Moritz, Jörg Meyer