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» Protein Model Representation and Construction
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CORR
2009
Springer
106views Education» more  CORR 2009»
13 years 6 months ago
A framework for protein and membrane interactions
dels at different abstraction levels; in particular, higher-level (e.g. membrane) activities can be given a formal biological justification in terms of low-level (i.e., protein) in...
Giorgio Bacci, Davide Grohmann, Marino Miculan
RECOMB
2008
Springer
14 years 9 months ago
Algorithms for Joint Optimization of Stability and Diversity in Planning Combinatorial Libraries of Chimeric Proteins
Abstract. In engineering protein variants by constructing and screening combinatorial libraries of chimeric proteins, two complementary and competing goals are desired: the new pro...
Wei Zheng, Alan M. Friedman, Chris Bailey-Kellogg
RECOMB
2004
Springer
14 years 9 months ago
Modeling and Analysis of Heterogeneous Regulation in Biological Networks
Abstract. In this study we propose a novel model for the representation of biological networks and provide algorithms for learning model parameters from experimental data. Our appr...
Irit Gat-Viks, Amos Tanay, Ron Shamir
BMCBI
2007
130views more  BMCBI 2007»
13 years 8 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
BIOINFORMATICS
2006
111views more  BIOINFORMATICS 2006»
13 years 8 months ago
Multiple Alignment of protein structures and sequences for VMD
Multiple Alignment is a new interface for performing and analyzing multiple protein structure alignments. It enables viewing levels of sequence and structure similarity on the ali...
John Eargle, Dan Wright, Zaida Luthey-Schulten