Recent techniques increase rapidly the amount of our knowledge on interactions between proteins. The interpretation of these new information depends on our ability to retrieve kno...
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
R. Henrik Nilsson, Balaji Rajashekar, Karl-Henrik ...
Molecular interaction databases can be used to study the evolution of molecular pathways across species. Querying such pathways is a challenging computational problem, and recent e...