Sequencing of peptides by tandem mass spectrometry has matured to the key technology for proteomics. Noise in the measurement process strongly favors statistical models like NovoHM...
Hansruedi Peter, Bernd Fischer, Joachim M. Buhmann
Background: In proteomics experiments, database-search programs are the method of choice for protein identification from tandem mass spectra. As amino acid sequence databases grow...
Jason W. H. Wong, Matthew J. Sullivan, Hugh M. Car...
Abstract. Database preprocessing in order to create an index often permits considerable speedup in search compared to the iterated query of an unprocessed database. In this paper w...
Background: Tandem mass spectrometry (MS/MS) has emerged as the leading method for high- throughput protein identification in proteomics. Recent technological breakthroughs have d...
Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational anal...