Background: Robustness of mathematical models of biochemical networks is important for validation purposes and can be used as a means of selecting between different competing mode...
— Models of biochemical reaction networks can be decomposed into a stoichiometric part and a kinetic part. The stoichiometric part describes the structural mass flows while the ...
Motivation: Most previous approaches to model biochemical networks havefocusedeither on the characterization of a networkstructurewith a number of components or on the estimation ...
Background: Sensitivity analysis is an indispensable tool for the analysis of complex systems. In a recent paper, we have introduced a thermodynamically consistent variance-based ...
Circadian clocks are biochemical networks, present in nearly all living organisms, whose function is to regulate the expression of specific mRNAs and proteins to synchronise rhyth...
Ozgur E. Akman, Federica Ciocchetta, Andrea Degasp...