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    BMCBI
    2007
    166views more  BMCBI 2007»
    PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
    13 years 7 months ago
    PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
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    Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
    Gürkan Bebek, Jiong Yang
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    BMCBI
    2007
    134views more  BMCBI 2007»
    Benchmarking natural-language parsers for biological applications using dependency graphs
    13 years 7 months ago
    Benchmarking natural-language parsers for biological applications using dependency graphs
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    Background: Interest is growing in the application of syntactic parsers to natural language processing problems in biology, but assessing their performance is difficult because di...
    Andrew B. Clegg, Adrian J. Shepherd
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    BMCBI
    2007
    97views more  BMCBI 2007»
    In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
    13 years 7 months ago
    In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
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    Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
    Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
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    BMCBI
    2008
    128views more  BMCBI 2008»
    Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
    13 years 7 months ago
    Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
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    Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
    Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
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    BMCBI
    2010
    123views more  BMCBI 2010»
    An improved classification of G-protein-coupled receptors using sequence-derived features
    13 years 7 months ago
    An improved classification of G-protein-coupled receptors using sequence-derived features
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    Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
    Zhen-Ling Peng, Jian-Yi Yang, Xin Chen
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