The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving various...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
Recombination is an important evolutionary mechanism responsible for the genetic diversity in humans and other organisms. Recently, there has been extensive research on understandi...
Abstract. In order to guarantee that the optimal motif is found, traditional pattern-driven approaches perform an exhaustive search over all candidate motifs of length l. We develo...
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
There are many critical situations when one needs to rapidly identify an unidentified pathogen from among a given set of previously sequenced pathogens. DNA or RNA hybridization c...