109 search results - page 9 / 22 » Query3d: a new method for high-throughput analysis of functi... |
IJCNN
2006
IEEE
14 years 22 days ago
2006
IEEE
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...
BMCBI
2004
13 years 6 months ago
2004
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
RECOMB
2009
Springer
14 years 1 months ago
2009
Springer
This paper presents a new approach to site-directed recombination, swapping combinations of selected discontiguous fragments from a source protein in place of corresponding fragmen...
BMCBI
2007
13 years 6 months ago
2007
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
BMCBI
2010
13 years 6 months ago
2010
Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...