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BMCBI
2004
122views more  BMCBI 2004»
13 years 7 months ago
A comprehensive comparison of comparative RNA structure prediction approaches
Background: An increasing number of researchers have released novel RNA structure analysis and prediction algorithms for comparative approaches to structure prediction. Yet, indep...
Paul P. Gardner, Robert Giegerich
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
BMCBI
2006
141views more  BMCBI 2006»
13 years 7 months ago
Identification of consensus RNA secondary structures using suffix arrays
Background: The identification of a consensus RNA motif often consists in finding a conserved secondary structure with minimum free energy in an ensemble of aligned sequences. How...
Mohammad Anwar, Truong Nguyen, Marcel Turcotte
BMCBI
2004
151views more  BMCBI 2004»
13 years 7 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
BMCBI
2007
87views more  BMCBI 2007»
13 years 7 months ago
A manually curated database of tetrapod mitochondrially encoded tRNA sequences and secondary structures
Background: Mitochondrial tRNAs have been the subject of study for structural biologists interested in their secondary structure characteristics, evolutionary biologists have rese...
Konstantin Yu Popadin, Leila A. Mamirova, Fyodor A...