Abstract. Conserved regions, or motifs, present among RNA secondary structures serve as a useful indicator for predicting the functionality of the RNA molecules. Automated detectio...
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
Ribonucleic acid (RNA) is a polymer composed of four bases denoted A, C, G, and U. It is a generally single-stranded molecule where the bases form hydrogen bonds within the same m...
Abstract One approach to predict the secondary structure of RNA is the comparative approach. This approach is used when alignment of several homologous sequences of a RNA is availa...