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BMCBI
2007
115views more  BMCBI 2007»
13 years 10 months ago
A novel, fast, HMM-with-Duration implementation - for application with a new, pattern recognition informed, nanopore detector
Background: Hidden Markov Models (HMMs) provide an excellent means for structure identification and feature extraction on stochastic sequential data. An HMM-with-Duration (HMMwD) ...
Stephen Winters-Hilt, Carl Baribault
BMCBI
2005
90views more  BMCBI 2005»
13 years 10 months ago
An algorithm for the determination and quantification of components of nucleic acid mixtures based on single sequencing reaction
Background: Determination and quantification of nucleic acid components in a mixture is usually accomplished by microarray approaches, where the mixtures are hybridized against sp...
Alexander E. Pozhitkov, Kathryn Stemshorn, Diethar...
JCC
2007
82views more  JCC 2007»
13 years 10 months ago
Peptide reagent design based on physical and chemical properties of amino acid residues
: It has tremendous values for both drug discovery and basic research to develop a solid bioinformatical tool for guiding peptide reagent design. Based on the physical and chemical...
Qishi Du, Ri-Bo Huang, Yu-Tuo Wei, Cheng-Hua Wang,...
JBCB
2010
123views more  JBCB 2010»
13 years 8 months ago
Characterizing the Space of interatomic Distance Distribution Functions Consistent with Solution Scattering Data
: Scattering of neutrons and x-rays from molecules in solution offers alternative approaches to the studying of a wide range of macromolecular structures in their solution state w...
Paritosh A. Kavathekar, Bruce A. Craig, Alan M. Fr...
BMCBI
2011
13 years 5 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...