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187
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BMCBI
2010
153views more  BMCBI 2010»
15 years 4 months ago
MimoSA: a system for minimotif annotation
Background: Minimotifs are short peptide sequences within one protein, which are recognized by other proteins or molecules. While there are now several minimotif databases, they a...
Jay Vyas, Ronald J. Nowling, Thomas Meusburger, Da...
BMCBI
2010
139views more  BMCBI 2010»
15 years 4 months ago
RNAstructure: software for RNA secondary structure prediction and analysis
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...
Jessica S. Reuter, David H. Mathews
139
Voted
BMCBI
2010
138views more  BMCBI 2010»
15 years 4 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
BMCBI
2010
125views more  BMCBI 2010»
15 years 4 months ago
Visualisation tool for peptide fractionation data in proteomics: application to OFFGEL isoelectric focussing
Background: OFFGEL isoelectric focussing (IEF) has become a popular tool in proteomics to fractionate peptides or proteins. As a consequence there is a need for software solutions...
David-Olivier D. Azulay, Hendrik Neubert, Mireia F...
BMCBI
2007
103views more  BMCBI 2007»
15 years 4 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang