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BMCBI
2011
13 years 4 months ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
BMCBI
2011
13 years 4 months ago
Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
Zsuzsanna Sukosd, Bjarne Knudsen, Morten Vaerum, J...
CORR
2011
Springer
174views Education» more  CORR 2011»
13 years 1 months ago
GPS Signal Acquisition via Compressive Multichannel Sampling
In this paper, we propose an efficient acquisition scheme for GPS receivers. It is shown that GPS signals can be effectively sampled and detected using a bank of randomized corre...
Xiao Li, Andrea Rueetschi, Yonina C. Eldar, Anna S...
MMM
2011
Springer
244views Multimedia» more  MMM 2011»
13 years 1 months ago
Shape Stylized Face Caricatures
Facial caricatures exaggerate key features to emphasize unique structural and personality traits. It is quite a challenge to retain the identity of the original person despite the ...
Nguyen Kim Hai Le, Why Yong Peng, Golam Ashraf
BIOINFORMATICS
2011
13 years 1 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
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