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» Reconstructing the pre-doubling genome
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BMCBI
2011
13 years 1 months ago
New Words in Human Mutagenesis
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
Alexander Y. Panchin, Sergey I. Mitrofanov, Andrei...
RECOMB
2005
Springer
14 years 10 months ago
Reconstruction of Reticulate Networks from Gene Trees
Abstract. One of the simplest evolutionary models has molecular sequences evolving from a common ancestor down a bifurcating phylogenetic tree, experiencing point-mutations along t...
Daniel H. Huson, Tobias H. Klöpper, Pete J. L...
BMCBI
2010
164views more  BMCBI 2010»
13 years 10 months ago
Flexible network reconstruction from relational databases with Cytoscape and CytoSQL
Background: Molecular interaction networks can be efficiently studied using network visualization software such as Cytoscape. The relevant nodes, edges and their attributes can be...
Kris Laukens, Jens Hollunder, Thanh Hai Dang, Geer...
BMCBI
2007
165views more  BMCBI 2007»
13 years 9 months ago
Automatic reconstruction of a bacterial regulatory network using Natural Language Processing
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
Carlos Rodríguez Penagos, Heladia Salgado, ...
FCCM
2007
IEEE
117views VLSI» more  FCCM 2007»
14 years 4 months ago
FPGA Acceleration of Gene Rearrangement Analysis
In this paper we present our work toward FPGA acceleration of phylogenetic reconstruction, a type of analysis that is commonly performed in the fields of systematic biology and co...
Jason D. Bakos