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» Reconstructing the pre-doubling genome
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NAR
1998
76views more  NAR 1998»
13 years 9 months ago
U-insertion/deletion Edited Sequence Database
Uridine insertion/deletion RNA editing is a posttranscriptional RNA modification occurring in the mitochondria of kinetoplastid protozoa. The U-insertion/ deletion Edited Sequence...
Larry Simpson, Shirley H. Wang, Otavio H. Thiemann...
RECOMB
2004
Springer
14 years 10 months ago
The Statistical Significance of Max-Gap Clusters
Identifying gene clusters, genomic regions that share local similarities in gene organization, is a prerequisite for many different types of genomic analyses, including operon pred...
Rose Hoberman, David Sankoff, Dannie Durand
BMCBI
2007
162views more  BMCBI 2007»
13 years 10 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2006
143views more  BMCBI 2006»
13 years 10 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2006
102views more  BMCBI 2006»
13 years 10 months ago
SNA - a toolbox for the stoichiometric analysis of metabolic networks
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
Robert Urbanczik