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» Reconstruction Using Witness Complexes
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RECOMB
2006
Springer
14 years 9 months ago
Identifiability Issues in Phylogeny-Based Detection of Horizontal Gene Transfer
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). Detecting this process bears great significanc...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
CVPR
2010
IEEE
14 years 4 months ago
Parametric Dimensionality Reduction by Unsupervised Regression
We introduce a parametric version (pDRUR) of the recently proposed Dimensionality Reduction by Unsupervised Regression algorithm. pDRUR alternately minimizes reconstruction error ...
Miguel Carreira-perpinan, Zhengdong Lu
BMCBI
2010
125views more  BMCBI 2010»
13 years 8 months ago
Compartmentalization of the Edinburgh Human Metabolic Network
Background: Direct in vivo investigation of human metabolism is complicated by the distinct metabolic functions of various sub-cellular organelles. Diverse micro-environments in d...
Tong Hao, Hongwu Ma, Xue-Ming Zhao, Igor Goryanin
BMCBI
2008
104views more  BMCBI 2008»
13 years 8 months ago
Comparison of methods for estimating the nucleotide substitution matrix
Background: The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different math...
Maribeth Oscamou, Daniel McDonald, Von Bing Yap, G...
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...