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» Regression analysis of multiple protein structures
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BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
Identifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Ki
Background: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure ...
Jenny Gu, Philip E. Bourne
BMCBI
2006
134views more  BMCBI 2006»
13 years 7 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
CLEF
2009
Springer
13 years 8 months ago
Morphological Analysis by Multiple Sequence Alignment
In biological sequence processing, Multiple Sequence Alignment (MSA) techniques capture information about long-distance dependencies and the three-dimensional structure of protein ...
Tzvetan Tchoukalov, Christian Monson, Brian Roark
NAR
2008
138views more  NAR 2008»
13 years 7 months ago
TarO: a target optimisation system for structural biology
TarO (http://www.compbio.dundee.ac.uk/taro) offers a single point of reference for key bioinformatics analyses relevant to selecting proteins or domains for study by structural bi...
Ian M. Overton, C. A. Johannes van Niekerk, Lester...
BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...